The Study of the Antimicrobial Properties of the Novel Cosmeceutical Remedy Components

Abstract

Based on the flora of Georgia the novel cosmeceutical remedy has been created by the composition of the plant substance "Melilot" (hereafter referred to as Melilot) and biocompatible, biodegradable amino acid polymer - film forming pseudoproteins (hereafter referred to as the polimer) [1-5].

The new cosmeceutical remedy will be a solid ointment for preventing any kind of scars and spots after plastic surgery and cosmetic procedures.

The selected plant raw materials for the preparation of "Melilot" has been collected in the field conditions. Aboveground part of during flowering: Melilotus offfiicinalis L. Trifolium praténse L. Chelidonium majus L. Unripe fruits Juglans regia L. and immature fruits (green) Maclura pomifera (Raf.) C.K.Schneid.

Each plant was processed separately, within a maximum of 72 hours after collection (refrigerated before processing). The plants were washed and dried, then homogenized at 45 – 50⁰ C, in the presence of conditionally alkaline mineral water (pH 7.1) to the consistency of porridge in the homogenizer. The homogenate was boiled for up to 5 minutes. Then,  95% ethyl alcohol was added to the homogenate and kept at 5⁰ C for 48 hours. The homogenate was dried and stored at 5⁰ C for 12 hours. The precipitate was removed by centrifugation at 4000 rpm for 10 min. The supernatant was filtered through a 5-8 μm vacuum filtration unit.