IMMUNOMODULATING EFFECT OF SAUMAL IN ATOPIC DERMATITIS

Abstract

Atopic dermatitis (AD) remains one of the most common chronic inflammatory and allergic skin diseases, characterised by recurrent episodes, severe itching, skin barrier dysfunction and reduced quality of life for patients. The pathogenesis of the disease is based on immune disorders, including a predominance of the Th2 response and increased production of immunoglobulin E. Despite the availability of standard therapeutic approaches, control of the disease often remains inadequate, and long-term use of medications is associated with the risk of side effects. In this regard, nutritional and non-drug methods with immunomodulatory potential are of particular interest.