The role of transarterial methods of treatment of patients with liver metastases

Abstract

Treatment of patients with metastatic liver disease remains a difficult task. It includes surgical and/or ablative (resection, local destruction, their combination, liver transplantation), X-ray endovascular methods (arterial embolization, chemo- and radioembolization) and systemic treatment (chemo-, bio-, targeted therapy, peptide-receptor radionuclide therapy). The choice of treatment tactics is determined by various factors: anatomical localization and relationship with neighboring organs, size and number of metastatic foci; severity of clinical manifestations due to the secretory activity of the tumor; degree of malignancy (Grade criterion). Less significant factors include age, concomitant pathology, localization of the primary tumor, the state of the liver parenchyma as a whole, the presence of cirrhosis, viral hepatitis B, C, etc.