CLINICOEPIDEMIOLOGICAL STUDY OF CELLULITIS THROUGH ALT-70 SCORING AND ERON SEVERITY INDICES WITH QUALITY-OF-LIFE CORRELATION

Abstract

Cellulitis is an acute bacterial infection involving the dermis and subcutaneous tissues, characterized by erythema, warmth, swelling, and tenderness of the affected area, most frequently the lower limbs. It is predominantly caused by Streptococcus pyogenes and Staphylococcus aureus, though polymicrobial infections may occur in immunocompromised individuals. Despite advancements in antimicrobial therapy, cellulitis continues to impose a significant clinical and economic burden due to its recurrence and potential complications such as abscess formation and lymphangitis. The present manuscript provides a comprehensive review of the etiology, pathophysiology, clinical manifestations, diagnostic modalities, and management strategies for cellulitis, integrating both pharmacological and non-pharmacological perspectives. Literature from PubMed, ScienceDirect, and other scientific databases was critically analysed to summarize contemporary evidence and guidelines. Management involves prompt initiation of empiric antibiotic therapy targeting gram-positive cocci, supported by wound care, skin hygiene, and the control of predisposing factors such as diabetes and obesity. Non-pharmacological interventions, including limb elevation, compression therapy, and proper moisturization, are equally essential in preventing recurrence and improving patient quality of life. A multidisciplinary and preventive approach emphasizing patient education, early diagnosis, and adherence to hygiene measures remains pivotal in reducing morbidity and recurrence rates. Thus, holistic management of cellulitis encompassing both pharmacologic precision and supportive care forms the cornerstone for improved therapeutic outcomes and sustainable infection control.