ISOLATION AND CHARACTERIZATION OF SALMONELLA STRAINS CIRCULATING IN POULTRY FARMS OF THE REPUBLIC OF KAZAKHSTAN

Abstract

This study investigates the isolation and characterization of Salmonella strains circulating in poultry farms across Kazakhstan, focusing on the pressing issue of antibiotic resistance. Salmonellosis, a significant public health concern, particularly in poultry farming, poses risks to both animal and human health due to the zoonotic transmission of resistant strains. Employing a combination of classical microbiological techniques and modern molecular methods, including selective media and MALDI-TOF mass spectrometry, the study identifies six Salmonella strains and assesses their resistance profiles against 30 antimicrobial agents. Results reveal alarming resistance, especially in multidrug-resistant (MDR) strains such as S. paratyphi C, highlighting a critical need for revised antimicrobial strategies in veterinary practice and public health. The findings underscore the importance of continuous surveillance, stricter regulations on antibiotic use in agriculture, and the exploration of non-antibiotic infection control methods. This research contributes vital data to the understanding of antibiotic resistance patterns in Kazakhstan, emphasizing the collaborative efforts required to combat this growing threat to public health and agricultural stability.