David Aphkhazava; Maia Nozadze; Levan Gulua; Mzia Tsiklauri; Manana Makharadze; Maia Berodze; Nodar Sulashvili; Giorgi Margvelani; Tamuna Samadashvili; Nino Maziashvili; Lolita Shengelia; Ridhwan Yoonus; Anupreet Kamble; George Maglakelidze; Ilia Atanelishvili. Ultra-Rare and Hyper-Rare Genetic Diseases at the Edge of Discovery: Molecular Mechanisms, Epidemiology, Genomic Architecture, and Translational Challenges. WSR 2026.